Here's the setup I use on smurf:
http://auno.org/ao/equip.php?saveid=197283
Learn from my mistakes so you don't repeat them:
1HB/1HE is annoying as fuck:
* you got mixed damage types
* if you use a 300 axe, you need to perk all the way into 1HB AND 1HE to keep them both out of OE
* you get 5 perks for defence which is really limiting - can't use coon and CH, I use CH but I ache for coon
* you have to use a whack of annoying gear to keep your weaps out of OE (trying to keep axe out of OE is painful)
I do want to redo smurf - if I retwinked him I would either choose 2HE with Honed edge of tarasque, or dual 1HB with DB Panther+300 Panther MK6.
Either setup will be decent damage, but more importantly it'll free up a lot of perks for defence, which means I could use either coon or Form of troll or Manners of Mongo. Either of these opens up some significant bonuses.
The 1HE /1HB setup is good for DPS, and there's no question about that, with 6 damage perks chained I can quickly and easily establish aggro. But quite frankly, it's not really needed. I'd rather use a more crit oriented setup (+15% scope) and rage in S7 to keep high DPS, especially with Panther bashing out 4.5k-5k crits.
Honed edge of tarasque would similarly produce pretty monster damage with massive normal/crit damage and procs for a 35s dot doing 1840 damage. In normal continuous play you'd likely have that proc going continuously I think.
Furthermore, 2HE perks do quite good damage. 1HB perks are very strong as well, so that's certainly a consideration.
The last point of consideration which is more significant than you may realise is what the attack time is on any weapon. DB panther requires ALL fast attack research to cap fast attack at 6.4s, whereas, axes- if you were considering them, do not require any research to cap fast attack recharge, which means you can get up to max DD faster with axes, then 2HE and 1HB.
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